Target：Gα 14

Fields：Calcium signaling pathway;Chagas disease;Amoebiasis

Gene Name：GNA14

Protein Name：Guanine nucleotide-binding protein subunit alpha-14

Human Gene Id：9630

Human Swiss Prot No：O95837

Mouse Gene Id：14675

Mouse Swiss Prot No：P30677

Immunogen：The antiserum was produced against synthesized peptide derived from human GNA14. AA range:1-50

Specificity：Gα 14 Polyclonal Antibody detects endogenous levels of Gα 14 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GNA14;Guanine nucleotide-binding protein subunit alpha-14;G alpha-14;G-protein subunit alpha-14

Observed Band(KD)：42kD

Background： This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009],

Function：function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,

Subcellular Location：heterotrimeric G-protein complex,plasma membrane,extracellular exosome,

Expression： Caudate nucleus,Pancreas,Spleen,