Target:Gz-α
Fields:Long-term depression
Gene Name:GNAZ
Protein Name:Guanine nucleotide-binding protein G(z) subunit alpha
Human Gene Id:2781
Human Swiss Prot No:P19086
Mouse Gene Id:14687
Mouse Swiss Prot No:O70443
Rat Gene Id:25740
Rat Swiss Prot No:P19627
Immunogen:The antiserum was produced against synthesized peptide derived from human Gz-alpha. AA range:1-50
Specificity:Gz-α Polyclonal Antibody detects endogenous levels of Gz-α protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GNAZ;Guanine nucleotide-binding protein G(z) subunit alpha;G(x) alpha chain;Gz-alpha
Observed Band(KD):41kD
Background:G protein subunit alpha z(GNAZ) Homo sapiens The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008],
Function:function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
Subcellular Location:Membrane; Lipid-anchor.
Expression: Brain,PNS,