Target：GPR75

Gene Name：GPR75

Protein Name：Probable G-protein coupled receptor 75

Human Gene Id：10936

Human Swiss Prot No：O95800

Mouse Gene Id：237716

Mouse Swiss Prot No：Q6X632

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430

Specificity：GPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GPR75;Probable G-protein coupled receptor 75

Observed Band(KD)：59kD

Background： GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002],

Function：function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.,

Subcellular Location：Cell membrane; Multi-pass membrane protein .

Expression：Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).