Target：GPR61

Gene Name：GPR61 BALGR

Protein Name：Probable G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor)

Human Gene Id：83873

Human Swiss Prot No：Q9BZJ8

Mouse Swiss Prot No：Q8C010

Immunogen：Synthesized peptide derived from human protein . at AA range: 190-270

Specificity：GPR61 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：49kD

Background： This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008],

Function：function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus. Also expressed in testis. Low expression in many other tissues.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538). .

Expression：Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level).