Target：GPR6

Gene Name：GPR6

Protein Name：G-protein coupled receptor 6 (Sphingosine 1-phosphate receptor GPR6)

Human Gene Id：2830

Human Swiss Prot No：P46095

Mouse Swiss Prot No：Q6YNI2

Rat Swiss Prot No：P51651

Immunogen：Synthesized peptide derived from human protein . at AA range: 290-370

Specificity：GPR6 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：39kD

Background：function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Function：function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.

Expression： Brain,