Target：GPR50

Fields：Neuroactive ligand-receptor interaction

Gene Name：GPR50

Protein Name：Melatonin-related receptor

Human Gene Id：9248

Human Swiss Prot No：Q13585

Mouse Swiss Prot No：O88495

Immunogen：The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350

Specificity：GPR50 Polyclonal Antibody detects endogenous levels of GPR50 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GPR50;Melatonin-related receptor;G protein-coupled receptor 50;H9

Observed Band(KD)：68kD

Background： This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],

Function：function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Hypothalamus and pituitary.