Target：GPR48

Fields：Wnt signaling pathway

Gene Name：LGR4

Protein Name：Leucine-rich repeat-containing G-protein coupled receptor 4

Human Gene Id：55366

Human Swiss Prot No：Q9BXB1

Mouse Swiss Prot No：A2ARI4

Immunogen：The antiserum was produced against synthesized peptide derived from human LGR4. AA range:461-510

Specificity：GPR48 Polyclonal Antibody detects endogenous levels of GPR48 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：LGR4;GPR48;Leucine-rich repeat-containing G-protein coupled receptor 4;G-protein coupled receptor 48

Observed Band(KD)：100kD

Background： The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016],

Function：function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 15 LRR (leucine-rich) repeats.,tissue specificity:Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.