Target：GPR133

Gene Name：GPR133

Protein Name：Probable G-protein coupled receptor 133

Human Gene Id：283383

Human Swiss Prot No：Q6QNK2

Mouse Swiss Prot No：Q80T32

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510

Specificity：GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GPR133;PGR25;Probable G-protein coupled receptor 133;G-protein coupled receptor PGR25

Observed Band(KD)：96kD

Background： The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010],

Function：function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Up-regulated in CD133(+) cell population of glioblastoma.