Target：GPR116

Gene Name：GPR116

Protein Name：Probable G-protein coupled receptor 116

Human Gene Id：221395

Human Swiss Prot No：Q8IZF2

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR116. AA range:11-60

Specificity：GPR116 Polyclonal Antibody detects endogenous levels of GPR116 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GPR116;KIAA0758;Probable G-protein coupled receptor 116

Observed Band(KD)：150kD

Background：function:May have a role in the regulation of acid-base balance.,PTM:Proteolytically cleaved into 2 highly conserved sites: one in the SEA domain and the other in the stalk domain region preceding the first transmembrane. The later 2 subunits, the extracellular subunit and the seven-transmembrane subunit, remain tightly associated and non-covalently linked.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 SEA domain.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Exists as disulfide-linked dimers at the cell surface.,

Function：function:May have a role in the regulation of acid-base balance.,PTM:Proteolytically cleaved into 2 highly conserved sites: one in the SEA domain and the other in the stalk domain region preceding the first transmembrane. The later 2 subunits, the extracellular subunit and the seven-transmembrane subunit, remain tightly associated and non-covalently linked.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 SEA domain.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Exists as disulfide-linked dimers at the cell surface.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression： Brain,Plasma,Testis,