Rabbit pAb

Catalog No.	QYA10801
Size.	100ug
Gene Name.	AP1M2
Protein Name.	AP1M2
Source.	Rabbit
Immunogen.	Synthesized peptide derived from human AP1M2
Purification.	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Specificity.	This antibody detects endogenous levels of AP1M2 at Human/Mouse
Formulation.	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration.	1 mg/ml
Storage / Stability.	-20°C/1 year
Human Gene ID.	10053
Human Swiss-Prot No.	Q9Y6Q5
Mouse Gene ID.	11768
Mouse Swiss-Prot No.	Q9WVP1
Rat Gene ID.
Rat Swiss-Prot No.
Reactivity.	Human, Mouse
Applications.	wb
Predicted band (Da)	46530
Observed band (KDa)	46530
Dilution.	WB 1：500-2000
Background.	This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], Function：function:Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.,PTM:Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.,similarity:Belongs to the adaptor complexes medium subunit family.,similarity:Contains 1 MHD (mu homology) domain.,subcellular location:Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.,subunit:Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or A Subcellular Location：ane,lysosomal membrane,cytosol,clathrin adaptor complex,cytoplasmic vesicle membrane,clathrin-coated endocytic vesicle membrane,trans-rk membrane,intracellular membrane-bounded organelle,