Target:USF-2
Gene Name:USF2
Protein Name:Upstream stimulatory factor 2
Human Gene Id:7392
Human Swiss Prot No:Q15853
Mouse Gene Id:22282
Mouse Swiss Prot No:Q64705
Rat Gene Id:81817
Rat Swiss Prot No:Q63665
Immunogen:The antiserum was produced against synthesized peptide derived from human USF2. AA range:196-245
Specificity:USF-2 Polyclonal Antibody detects endogenous levels of USF-2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:USF2;BHLHB12;Upstream stimulatory factor 2;Class B basic helix-loop-helix protein 12;bHLHb12;FOS-interacting protein;FIP;Major late transcription factor 2;Upstream transcription factor 2
Observed Band(KD):40kD
Background: This gene encodes a member of the basic helix-loop-helix leucine zipper family of transcription factors. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes. [provided by RefSeq, Mar 2016],
Function:alternative products:Additional isoforms seem to exist,function:Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with MAF (By similarity). Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). In vivo, the USF1/USF2A heterodimer represents over 66% of the usf binding activity whereas the USF1 and USF2A homodimers represent less than 10%. The USF1/USF2B heterodimer accounted for almost 15% in some cell.,tissue specificity:Ubiquitous.,
Subcellular Location:Nucleus.
Expression:Ubiquitous.