Target：Urotensin II

Fields：Neuroactive ligand-receptor interaction

Gene Name：UTS2

Protein Name：Urotensin-2

Human Gene Id：10911

Human Swiss Prot No：O95399

Mouse Swiss Prot No：Q9QZQ3

Immunogen：The antiserum was produced against synthesized peptide derived from human Urotensin II. AA range:48-97

Specificity：Urotensin II Polyclonal Antibody detects endogenous levels of Urotensin II protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：UTS2;Urotensin-2;Urotensin II;U-II;UII

Observed Band(KD)：14kD

Background： This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Function：function:Highly potent vasoconstrictor.,similarity:Belongs to the urotensin-2 family.,tissue specificity:Brain specific.,

Subcellular Location：Secreted.

Expression：Brain specific.