Target：UMP-CMP Kinase

Fields：Pyrimidine metabolism;Drug metabolism - other enzymes;Metabolic pathways;Nucleotide metabolism;Biosynthesis of cofactors

Gene Name：CMPK1

Protein Name：UMP-CMP kinase

Human Gene Id：51727

Human Swiss Prot No：P30085

Mouse Gene Id：66588

Mouse Swiss Prot No：Q9DBP5

Rat Gene Id：298410

Rat Swiss Prot No：Q4KM73

Immunogen：The antiserum was produced against synthesized peptide derived from human KCY. AA range:1-50

Specificity：UMP-CMP Kinase Polyclonal Antibody detects endogenous levels of UMP-CMP Kinase protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CMPK1;CMK;CMPK;UCK;UMK;UMPK;UMP-CMP kinase;Cytidine monophosphate kinase;Cytidylate kinase;Deoxycytidylate kinase;Uridine monophosphate kinase;Uridine monophosphate/cytidine monophosphate kinase;UMP/CMP kinase;UMP/CMPK

Observed Band(KD)：22kD

Background： This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012],

Function：catalytic activity:ATP + (d)CMP = ADP + (d)CDP.,cofactor:Magnesium.,function:Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.,similarity:Belongs to the adenylate kinase family.,subcellular location:Mainly nuclear.,tissue specificity:Ubiquitously expressed.,

Subcellular Location：Nucleus . Cytoplasm . Predominantly cytoplasmic, less than 15% nuclear. .

Expression：Ubiquitously expressed.