Target:CNDP2
Fields:Arginine and proline metabolism;Histidine metabolism;beta-Alanine metabolism;Metabolic pathways
Gene Name:CNDP2 CN2 CPGL PEPA
Protein Name:Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A)
Human Gene Id:55748
Human Swiss Prot No:Q96KP4
Mouse Swiss Prot No:Q9D1A2
Rat Swiss Prot No:Q6Q0N1
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:CNDP2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):52kD
Background:CNDP dipeptidase 2 (metallopeptidase M20 family)(CNDP2) Homo sapiens CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008],
Function:cofactor:Binds 2 zinc ions per subunit.,similarity:Belongs to the peptidase M20A family.,
Subcellular Location:Cytoplasm .
Expression:[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). ; [Isoform 2]: Broadly expressed in fetal tissues. Expressed in adult liver and placenta.