Target：CHST13

Fields：Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Gene Name：CHST13

Protein Name：Carbohydrate sulfotransferase 13

Human Gene Id：166012

Human Swiss Prot No：Q8NET6

Immunogen：The antiserum was produced against synthesized peptide derived from human CHST13. AA range:211-260

Specificity：CHST13 Polyclonal Antibody detects endogenous levels of CHST13 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CHST13;Carbohydrate sulfotransferase 13;Chondroitin 4-O-sulfotransferase 3;Chondroitin 4-sulfotransferase 3;C4ST-3;C4ST3

Observed Band(KD)：39kD

Background： The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011],

Function：catalytic activity:3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.,function:Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney.,

Subcellular Location：Golgi apparatus membrane ; Single-pass type II membrane protein .

Expression：Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney.