Target：Lymphotactin

Fields：Cytokine-cytokine receptor interaction;Viral protein interaction with cytokine and cytokine receptor;Chemokine signaling pathway

Gene Name：XCL1/XCL2

Protein Name：Lymphotactin/Cytokine SCM-1 beta

Human Gene Id：6375

Human Swiss Prot No：P47992

Mouse Swiss Prot No：P47993

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human XCL1/XCL2. AA range:51-100

Specificity：Lymphotactin Polyclonal Antibody detects endogenous levels of Lymphotactin protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：XCL1;LTN;SCYC1;Lymphotactin;ATAC;C motif chemokine 1;Cytokine SCM-1;Lymphotaxin;SCM-1-alpha;Small-inducible cytokine C1;XC chemokine ligand 1;XCL2;SCYC2;Cytokine SCM-1 beta;C motif chemokine 2;XC chemokine ligand 2

Observed Band(KD)：25kD

Background： This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014],

Function：function:Chemotactic activity for lymphocytes but not for monocytes or neutrophils.,online information:XCL1 entry,similarity:Belongs to the intercrine gamma family.,tissue specificity:Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.,

Subcellular Location：Secreted.

Expression：Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.