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CD85g Polyclonal Antibody
CD85g Polyclonal Antibody
CD85g Polyclonal Antibody
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商品描述

商品属性

Target:CD85g

Fields:Osteoclast differentiation;B cell receptor signaling pathway

Gene Name:LILRA4

Protein Name:Leukocyte immunoglobulin-like receptor subfamily A member 4

Human Gene Id:23547

Human Swiss Prot No:P59901

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA4. AA range:391-440

Specificity:CD85g Polyclonal Antibody detects endogenous levels of CD85g protein.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source:Polyclonal, Rabbit,IgG

Dilution:WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/ml

Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name:LILRA4;ILT7;Leukocyte immunoglobulin-like receptor subfamily A member 4;CD85 antigen-like family member G;Immunoglobulin-like transcript 7;ILT-7;CD85g

Observed Band(KD):55kD

Background: This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015],

Function:function:May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected on eosinophils, neutrophils and monocytes.,

Subcellular Location:Cell membrane ; Single-pass type I membrane protein .

Expression:Detected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells.

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