Target：CD80
Fields：Cell adhesion molecules;Toll-like receptor signaling pathway;Intestinal immune network for IgA production;Type I diabetes mellitus;Autoimmune thyroid disease;Systemic lupus erythematosus;Rheumatoid arthritis;Allograft rejection;Graft-versus-host disease;Viral myocarditis
Gene Name：CD80 CD28LG CD28LG1 LAB7
Protein Name：T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)
Human Gene Id：941
Human Swiss Prot No：P33681
Mouse Gene Id：12519
Mouse Swiss Prot No：Q00609
Immunogen：Synthetic peptide from human protein at AA range: 100-160
Specificity：The antibody detects endogenous CD80
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80)
Background： The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],
Function：function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,
Subcellular Location：Membrane; Single-pass type I membrane protein.
Expression：Expressed on activated B-cells, macrophages and dendritic cells.
