Target：CD300f

Gene Name：CD300LF

Protein Name：CMRF35-like molecule 1

Human Gene Id：146722

Human Swiss Prot No：Q8TDQ1

Mouse Gene Id：246746

Mouse Swiss Prot No：Q6SJQ7

Rat Gene Id：287818

Rat Swiss Prot No：Q566E6

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CD300LF. AA range:41-90

Specificity：CD300f Polyclonal Antibody detects endogenous levels of CD300f protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CD300LF;CD300F;CLM1;IGSF13;IREM1;NKIR;CMRF35-like molecule 1;CLM-1;CD300 antigen-like family member F;Immune receptor expressed on myeloid cells 1;IREM-1;Immunoglobulin superfamily member 13;IgSF13;NK inhibitory receptor;CD300f

Observed Band(KD)：32kD

Background： This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Function：function:Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with PTPN6/SHP-1 in a tyrosine phosphorylation dependent manner.,tissue specificity:Highly expressed in spleen, peripheral blood leukocte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression：Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.