Target：CD272

Gene Name：BTLA

Protein Name：B- and T-lymphocyte attenuator

Human Gene Id：151888

Human Swiss Prot No：Q7Z6A9

Mouse Swiss Prot No：Q7TSA3

Immunogen：Synthetic peptide from human protein at AA range: 101-150

Specificity：CD272 Polyclonal Antibody detects endogenous levels of CD272 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BTLA;B- and T-lymphocyte attenuator;B- and T-lymphocyte-associated protein;CD antigen CD272

Observed Band(KD)：36kD

Background： This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],

Function：function:Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.,PTM:N-glycosylated.,PTM:Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Interacts with TNFRSF14/HVEM.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression： PCR rescued clones,Peripheral blood,Thymus,Trachea,