Target：CD235a
Fields：Hematopoietic cell lineage;Malaria
Gene Name：GYPA
Protein Name：Glycophorin-A
Human Gene Id：2993
Human Swiss Prot No：P02724
Mouse Gene Id：14934
Mouse Swiss Prot No：P14220
Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human GYPA. AA range:41-90
Specificity：CD235a Polyclonal Antibody detects endogenous levels of CD235a protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：GYPA;GPA;Glycophorin-A;MN sialoglycoprotein;PAS-2;Sialoglycoprotein alpha;CD235a
Observed Band(KD)：16kD
Background： Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008],
Function：function:Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.,online information:Blood group antigen gene mutation database,polymorphism:Along with GYPB, GYPA is responsible for the MNS blood group system.,similarity:Belongs to the glycophorin A family.,
Subcellular Location：Cell membrane ; Single-pass type I membrane protein . Appears to be colocalized with SLC4A1.
Expression： Blood,Bone marrow,Kidney,Liver,Lung,Miltenberger class V,
