Target:CD229
Gene Name:LY9
Protein Name:T-lymphocyte surface antigen Ly-9
Human Gene Id:4063
Human Swiss Prot No:Q9HBG7
Mouse Gene Id:17085
Mouse Swiss Prot No:Q01965
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human LY9. AA range:261-310
Specificity:CD229 Polyclonal Antibody detects endogenous levels of CD229 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:LY9;CDABP0070;T-lymphocyte surface antigen Ly-9;Cell surface molecule Ly-9;Lymphocyte antigen 9;CD229
Observed Band(KD):72kD
Background: LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008],
Function:alternative products:Experimental confirmation may be lacking for some isoforms,function:May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
Subcellular Location:Membrane; Single-pass type I membrane protein. Cell membrane .
Expression:Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.