Target:CD225
Fields:B cell receptor signaling pathway
Gene Name:IFITM1
Protein Name:Interferon-induced transmembrane protein 1
Human Gene Id:8519
Human Swiss Prot No:P13164
Mouse Gene Id:68713
Mouse Swiss Prot No:Q9D103
Immunogen:The antiserum was produced against synthesized peptide derived from the N-terminal region of human IFITM1. AA range:1-50
Specificity:CD225 Polyclonal Antibody detects endogenous levels of CD225 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:IFITM1;CD225;IFI17;Interferon-induced transmembrane protein 1;Dispanin subfamily A member 2a;DSPA2a;Interferon-induced protein 17;Interferon-inducible protein 9-27;Leu-13 antigen;CD225
Observed Band(KD):15kD
Background:function:Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.,induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
Function:function:Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.,induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
Subcellular Location:Cell membrane ; Single-pass membrane protein . Lysosome membrane .
Expression:Bone (at protein level). Levels greatly elevated in colon cancer, cervical cancer, esophageal cancer and ovarian cancer. Expressed in glioma cell lines.