Target：Casein Kinase Iγ1
Fields：Hedgehog signaling pathway
Gene Name：CSNK1G1
Protein Name：Casein kinase I isoform gamma-1
Human Gene Id：53944
Human Swiss Prot No：Q9HCP0
Mouse Gene Id：214897
Mouse Swiss Prot No：Q8BTH8
Rat Gene Id：64086
Rat Swiss Prot No：Q62761
Immunogen：The antiserum was produced against synthesized peptide derived from human CKI-gamma1. AA range:1-50
Specificity：Casein Kinase Iγ1 Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：CSNK1G1;Casein kinase I isoform gamma-1;CKI-gamma 1
Observed Band(KD)：49kD
Background： This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
Subcellular Location：Cytoplasm.
Expression： Brain,Muscle,Pooled,
