Target：CARF

Gene Name：CDKN2AIP CARF

Protein Name：CDKN2A-interacting protein (Collaborator of ARF)

Human Gene Id：55602

Human Swiss Prot No：Q9NXV6

Mouse Swiss Prot No：Q8BI72

Rat Swiss Prot No：Q5U2X0

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CARF Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：63kD

Background： The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

Function：function:Activates TP53/p53 by CDKN2A-dependent and CDKN2A-independent pathways.,PTM:May be ubiquitinated.,similarity:Belongs to the CARF family.,similarity:Contains 1 DRBM (double-stranded RNA-binding) domain.,subunit:Interacts with CDKN2A/p14ARF, TP53/p53 and MDM2.,tissue specificity:Ubiquitously expressed.,

Subcellular Location：Nucleus, nucleoplasm .

Expression：Ubiquitously expressed.