Target：CAN13

Gene Name：CAPN13

Protein Name：Calpain-13 (EC 3.4.22.-) (Calcium-activated neutral proteinase 13) (CANP 13)

Human Gene Id：92291

Human Swiss Prot No：Q6MZZ7

Mouse Swiss Prot No：Q3UW68

Rat Swiss Prot No：Q5BK10

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CAN13 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：73kD

Background： The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],

Function：caution:It is unlikely that this protein binds calcium as none of the 2 EF-hand domains seem to contain a canonical calcium-binding site.,function:Probable non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,tissue specificity:Weakly expressed in lung and testis. Weakly or not expressed in other tissues.,

Subcellular Location：intracellular,cytoplasm,

Expression：Weakly expressed in lung and testis. Weakly or not expressed in other tissues.