Target：CaMKIβ

Gene Name：PNCK

Protein Name：Calcium/calmodulin-dependent protein kinase type 1B

Human Gene Id：139728

Human Swiss Prot No：Q6P2M8

Mouse Gene Id：93843

Mouse Swiss Prot No：Q9QYK9

Rat Gene Id：29660

Rat Swiss Prot No：O70150

Immunogen：The antiserum was produced against synthesized peptide derived from human CaMK1-beta. AA range:161-210

Specificity：CaMKIβ Polyclonal Antibody detects endogenous levels of CaMKIβ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PNCK;Calcium/calmodulin-dependent protein kinase type 1B;CaM kinase I beta;CaM kinase IB;CaM-KI beta;CaMKI-beta;Pregnancy up-regulated non-ubiquitously-expressed CaM kinase

Observed Band(KD)：38kD

Background： PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by Ca(2+)/calmodulin.,function:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.,PTM:Phosphorylated by CAMKK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,

Subcellular Location：Cytoplasm . Nucleus .

Expression： Brain,Liver,Placenta,Thalamus,