Target：BTF3

Gene Name：BTF3 NACB OK/SW-cl.8

Protein Name：Transcription factor BTF3 (RNA polymerase B transcription factor 3)

Human Gene Id：689

Human Swiss Prot No：P20290

Mouse Swiss Prot No：Q64152

Immunogen：Synthesized peptide derived from human protein . at AA range: 120-200

Specificity：BTF3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：22kD

Background： This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008],

Function：function:General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NAC-beta family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,

Subcellular Location：Cytoplasm . Nucleus . The heterodimer with NACA is cytoplasmic.

Expression： Colon adenocarcinoma,Leukocyte,Skin,