Target：BCLAF1

Gene Name：BCLAF1

Protein Name：Bcl-2-associated transcription factor 1

Human Gene Id：9774

Human Swiss Prot No：Q9NYF8

Mouse Gene Id：72567

Mouse Swiss Prot No：Q8K019

Immunogen：The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330

Specificity：BTF Polyclonal Antibody detects endogenous levels of BTF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BCLAF1;BTF;KIAA0164;Bcl-2-associated transcription factor 1;Btf

Observed Band(KD)：106kD

Background： This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Function：function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,

Subcellular Location：Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .

Expression：Ubiquitous.