Target：BRS-3

Fields：Neuroactive ligand-receptor interaction

Gene Name：BRS3

Protein Name：Bombesin receptor subtype-3

Human Gene Id：680

Human Swiss Prot No：P32247

Mouse Swiss Prot No：O54798

Immunogen：The antiserum was produced against synthesized peptide derived from human BRS3. AA range:161-210

Specificity：BRS-3 Polyclonal Antibody detects endogenous levels of BRS-3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BRS3;Bombesin receptor subtype-3;BRS-3

Observed Band(KD)：47kD

Background： The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011],

Function：function:Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:In germ cells in testis. Lung carcinoma cells.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：In germ cells in testis. Lung carcinoma cells.