Target：Brp44L

Fields：Diabetic cardiomyopathy

Gene Name：MPC1

Protein Name：Mitochondrial pyruvate carrier 1

Human Gene Id：51660

Human Swiss Prot No：Q9Y5U8

Mouse Gene Id：55951

Mouse Swiss Prot No：P63030

Rat Gene Id：171087

Rat Swiss Prot No：P63031

Immunogen：The antiserum was produced against synthesized peptide derived from human BRP44L. AA range:11-60

Specificity：Brp44L Polyclonal Antibody detects endogenous levels of Brp44L protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MPC1;BRP44L;CGI-129;HSPC040;PNAS-115;Mitochondrial pyruvate carrier 1;Brain protein 44-like protein

Observed Band(KD)：12kD

Background： The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012],

Function：similarity:Belongs to the UPF0041 (0-44) family.,

Subcellular Location：Mitochondrion inner membrane ; Multi-pass membrane protein .

Expression： Placenta,Promyelocytic leukemia,Skeletal muscle,Umbilical cord blood,