Target:BORA
Gene Name:BORA C13orf34
Protein Name:Protein aurora borealis (HsBora)
Human Gene Id:79866
Human Swiss Prot No:Q6PGQ7
Mouse Swiss Prot No:Q8BS90
Rat Swiss Prot No:Q5M864
Immunogen:Synthesized peptide derived from human protein . at AA range: 440-520
Specificity:BORA Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):61kD
Background: BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008],
Function:function:Required for the activation of Aurora-A (AURKA/STK6) at the onset of mitosis.,PTM:Phosphorylated by AURKA/STK6.,similarity:Belongs to the BORA family.,subunit:Interacts with AURKA/STK6.,
Subcellular Location:cytosol,meiotic spindle,
Expression: Bone marrow,Leiomyosarcoma,Rhabdomyosarcoma,Small intestine,Testis carcinom