Target：BMPER

Gene Name：BMPER KIAA1965

Protein Name：BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2)

Human Gene Id：168667

Human Swiss Prot No：Q8N8U9

Mouse Swiss Prot No：Q8CJ69

Immunogen：Synthesized peptide derived from human protein . at AA range: 440-520

Specificity：BMPER Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：75kD

Background： This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011],

Function：function:Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.,similarity:Contains 1 TIL (trypsin inhibitory-like) domain.,similarity:Contains 1 VWFD domain.,similarity:Contains 5 VWFC domains.,subunit:Interacts with BMP4.,tissue specificity:Highly expressed in lung, and brain and also in primary chondrocytes.,

Subcellular Location：Secreted .

Expression：Highly expressed in lung, and brain and also in primary chondrocytes.