Target:BMP-9
Fields:Cytokine-cytokine receptor interaction
Gene Name:GDF2 BMP9
Protein Name:Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
Human Gene Id:2658
Human Swiss Prot No:Q9UK05
Mouse Gene Id:12165
Mouse Swiss Prot No:Q9WV56
Immunogen:Synthetic peptide from human protein at AA range: 371-420
Specificity:The antibody detects endogenous BMP-9
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],
Function:function:Could be involved in bone formation.,online information:GDF2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
Subcellular Location:Secreted .
Expression:Detected in blood plasma (at protein level).