Target:BLBP
Fields:PPAR signaling pathway
Gene Name:FABP7 BLBP FABPB MRG
Protein Name:Fatty acid-binding protein, brain (Brain lipid-binding protein) (BLBP) (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Mammary-derived growth inhibitor related)
Human Gene Id:2173
Human Swiss Prot No:O15540
Mouse Gene Id:12140
Mouse Swiss Prot No:P51880
Rat Swiss Prot No:P55051
Immunogen:Synthetic peptide from human protein at AA range: 80-132
Specificity:The antibody detects endogenous BLBP
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000, ELISA 1:10000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:Fatty acid-binding protein, brain (Brain lipid-binding protein) (BLBP) (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Mammary-derived growth inhibitor related)
Observed Band(KD):15kD
Background: The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016],
Function:domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Expressed in brain and other neural tissues.,
Subcellular Location:Cytoplasm.
Expression:Expressed in brain and other neural tissues.