Target：MC5-R

Fields：Neuroactive ligand-receptor interaction

Gene Name：MC5R

Protein Name：Melanocortin receptor 5

Human Gene Id：4161

Human Swiss Prot No：P33032

Mouse Swiss Prot No：P41149

Rat Gene Id：25726

Rat Swiss Prot No：P35345

Immunogen：The antiserum was produced against synthesized peptide derived from human MC5R. AA range:271-320

Specificity：MC5-R Polyclonal Antibody detects endogenous levels of MC5-R protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MC5R;Melanocortin receptor 5;MC5-R;MC-2

Observed Band(KD)：40kD

Background： This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010],

Function：function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in the brain but not in the melanoma cells.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed in the brain but not in the melanoma cells.