Target：ATE1

Gene Name：ATE1

Protein Name：Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)

Human Gene Id：11101

Human Swiss Prot No：O95260

Mouse Swiss Prot No：Q9Z2A5

Immunogen：Synthesized peptide derived from human protein . at AA range: 400-480

Specificity：ATE1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：56kD

Background： This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Function：catalytic activity:L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.,caution:It is uncertain whether Met-1 or Met-37 is the initiator.,function:Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the R-transferase family.,subunit:Monomer .,

Subcellular Location：[Isoform ATE1-1]: Nucleus . Cytoplasm .; [Isoform ATE1-2]: Cytoplasm .

Expression： Embryonic kidney,Testis,