Target：MCT12
Gene Name：SLC16A12
Protein Name：Monocarboxylate transporter 12
Human Gene Id：387700
Human Swiss Prot No：Q6ZSM3
Mouse Gene Id：240638
Mouse Swiss Prot No：Q8BGC3
Immunogen：The antiserum was produced against synthesized peptide derived from human MOT12. AA range:115-164
Specificity：MCT12 Polyclonal Antibody detects endogenous levels of MCT12 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：SLC16A12;MCT12;Monocarboxylate transporter 12;MCT 12;Solute carrier family 16 member 12
Observed Band(KD)：53kD
Background： This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010],
Function：disease:Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.,
Subcellular Location：Cell membrane ; Multi-pass membrane protein .
Expression：Most highly expressed in kidney, followed by retina, lung, heart and testis. Very weakly expressed in brain and liver. Also detected in lens.
