Target：ARHGAP12

Gene Name：ARHGAP12

Protein Name：Rho GTPase-activating protein 12

Human Gene Id：94134

Human Swiss Prot No：Q8IWW6

Mouse Gene Id：75415

Mouse Swiss Prot No：Q8C0D4

Immunogen：Synthesized peptide derived from ARHGAP12 . at AA range: 310-390

Specificity：ARHGAP12 Polyclonal Antibody detects endogenous levels of ARHGAP12 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ARHGAP12;Rho GTPase-activating protein 12;Rho-type GTPase-activating protein 12

Observed Band(KD)：100kD

Background： This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],

Function：function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,

Subcellular Location：cytosol,

Expression： PCR rescued clones,Placenta,T-cell,Testis,Uterus,