Target：AOFB

Fields：Glycine, serine and threonine metabolism;Arginine and proline metabolism;Histidine metabolism;Tyrosine metabolism;Phenylalanine metabolism;Tryptophan metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Serotonergic synapse;Dopaminergic synapse;Parkinson disease;Cocaine addiction;Amphetamine addiction;Alcoholism

Gene Name：MAOB

Protein Name：Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)

Human Gene Id：4129

Human Swiss Prot No：P27338

Mouse Swiss Prot No：Q8BW75

Rat Swiss Prot No：P19643

Immunogen：Synthesized peptide derived from human protein . at AA range: Internal

Specificity：AOFB Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：57kD

Background： The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008],

Function：catalytic activity:RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2).,cofactor:FAD.,function:Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.,mass spectrometry: PubMed:11049757,online information:Monoamine oxidase entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the flavin monoamine oxidase family.,subunit:Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.,

Subcellular Location：Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

Expression： Brain,