Target：POPD1

Fields：Tight junction

Gene Name：BVES POP1 POPDC1

Protein Name：Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1)

Human Gene Id：11149

Human Swiss Prot No：Q8NE79

Mouse Swiss Prot No：Q9ES83

Rat Swiss Prot No：Q3BCU4

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：POPD1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：39kD

Background：blood vessel epicardial substance(BVES) Homo sapiens This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010],

Function：function:May play an important role in heart development.,similarity:Belongs to the popeye family.,tissue specificity:Expressed in fetal and adult heart and skeletal muscle.,

Subcellular Location：Lateral cell membrane . Cell junction, tight junction . Membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Membrane, caveola . Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells. .

Expression：Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.