Target:POLR3E
Fields:RNA polymerase;Cytosolic DNA-sensing pathway
Gene Name:POLR3E
Protein Name:DNA-directed RNA polymerase III subunit RPC5
Human Gene Id:55718
Human Swiss Prot No:Q9NVU0
Mouse Gene Id:26939
Mouse Swiss Prot No:Q9CZT4
Immunogen:The antiserum was produced against synthesized peptide derived from human RPC5. AA range:191-240
Specificity:POLR3E Polyclonal Antibody detects endogenous levels of POLR3E protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:POLR3E;KIAA1452;DNA-directed RNA polymerase III subunit RPC5;RNA polymerase III subunit C5;DNA-directed RNA polymerase III 80 kDa polypeptide
Observed Band(KD):80kD
Background:function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3D/RPC4.,
Function:function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3D/RPC4.,
Subcellular Location:Nucleus.
Expression: Brain,Eye,Liver,Teratocarcinoma,