Target：POLR3D

Fields：RNA polymerase;Cytosolic DNA-sensing pathway

Gene Name：POLR3D

Protein Name：DNA-directed RNA polymerase III subunit RPC4

Human Gene Id：661

Human Swiss Prot No：P05423

Mouse Gene Id：67065

Mouse Swiss Prot No：Q91WD1

Immunogen：The antiserum was produced against synthesized peptide derived from human RPC4. AA range:281-330

Specificity：POLR3D Polyclonal Antibody detects endogenous levels of POLR3D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：POLR3D;BN51;BN51T;DNA-directed RNA polymerase III subunit RPC4;RNA polymerase III subunit C4;DNA-directed RNA polymerase III subunit D;Protein BN51;RNA polymerase III 47 kDa subunit;RPC53 homolog

Observed Band(KD)：38kD

Background： This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008],

Function：function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.,similarity:Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3E/RPC5.,

Subcellular Location：Nucleus.

Expression： Epithelium,Lung,Lymph,