Target：PO3F2

Gene Name：POU3F2 BRN2 OCT7 OTF7

Protein Name：POU domain, class 3, transcription factor 2 (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2) (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Octamer-binding pro

Human Gene Id：5454

Human Swiss Prot No：P20265

Mouse Swiss Prot No：P31360

Rat Swiss Prot No：P56222

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：PO3F2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：48kD

Background： This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012],

Function：function:Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters.,similarity:Belongs to the POU transcription factor family. Class-3 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with PQBP1.,tissue specificity:Expressed specifically in the neuroectodermal cell lineage.,

Subcellular Location：Nucleus.

Expression：Expressed specifically in the neuroectodermal cell lineage.