Target：AVP Receptor V3
Fields：Calcium signaling pathway;Phospholipase D signaling pathway;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction
Gene Name：AVPR1B
Protein Name：Vasopressin V1b receptor
Human Gene Id：553
Human Swiss Prot No：P47901
Mouse Swiss Prot No：Q9WU02
Immunogen：The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324
Specificity：AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：AVPR1B;AVPR3;VPR3;Vasopressin V1b receptor;V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor
Observed Band(KD)：47kD
Background： The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
Function：function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location：Cell membrane ; Multi-pass membrane protein .
Expression： Lung carcinoma,Pituitary,
