Target：Ephrin-A3

Fields：MAPK signaling pathway;Ras signaling pathway;Rap1 signaling pathway;PI3K-Akt signaling pathway;Axon guidance;MicroRNAs in cancer

Gene Name：EFNA3

Protein Name：Ephrin-A3

Human Gene Id：1944

Human Swiss Prot No：P52797

Mouse Gene Id：13638

Mouse Swiss Prot No：O08545

Immunogen：The antiserum was produced against synthesized peptide derived from human EFNA3. AA range:161-210

Specificity：Ephrin-A3 Polyclonal Antibody detects endogenous levels of Ephrin-A3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EFNA3;EFL2;EPLG3;LERK3;Ephrin-A3;EFL-2;EHK1 ligand;EHK1-L;EPH-related receptor tyrosine kinase ligand 3;LERK-3

Observed Band(KD)：38kD

Background： This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the ephrin family.,tissue specificity:Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.,

Subcellular Location：Cell membrane; Lipid-anchor, GPI-anchor.

Expression：Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.