Target：EP2

Fields：cAMP signaling pathway;Neuroactive ligand-receptor interaction;Inflammatory mediator regulation of TRP channels;Renin secretion;Human cytomegalovirus infection;Pathways in cancer

Gene Name：PTGER2

Protein Name：Prostaglandin E2 receptor EP2 subtype

Human Gene Id：5732

Human Swiss Prot No：P43116

Mouse Gene Id：19217

Mouse Swiss Prot No：Q62053

Rat Gene Id：81752

Rat Swiss Prot No：Q62928

Immunogen：The antiserum was produced against synthesized peptide derived from human PE2R2. AA range:261-310

Specificity：EP2 Polyclonal Antibody detects endogenous levels of EP2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PTGER2;Prostaglandin E2 receptor EP2 subtype;PGE receptor EP2 subtype;PGE2 receptor EP2 subtype;Prostanoid EP2 receptor

Observed Band(KD)：40kD

Background： This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009],

Function：function:Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Placenta and lung.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Placenta and lung.