Target：EP15R

Fields：Endocytosis

Gene Name：EPS15L1 EPS15R

Protein Name：Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)

Human Gene Id：58513

Human Swiss Prot No：Q9UBC2

Mouse Swiss Prot No：Q60902

Immunogen：Synthesized peptide derived from human protein . at AA range: 350-430

Specificity：EP15R Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：95kD

Background：function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,

Function：function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,

Subcellular Location：Cell membrane ; Peripheral membrane protein . Nucleus . Membrane, coated pit . Localized to plasma membrane coated pits. .

Expression： Brain,Epithelium,Fetal brain,T-cell,Uterus,