Target：EOMES

Gene Name：EOMES

Protein Name：Eomesodermin homolog

Human Gene Id：8320

Human Swiss Prot No：O95936

Mouse Gene Id：13813

Mouse Swiss Prot No：O54839

Immunogen：The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108

Specificity：EOMES Polyclonal Antibody detects endogenous levels of EOMES protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EOMES;TBR2;Eomesodermin homolog;T-box brain protein 2;T-brain-2;TBR-2

Observed Band(KD)：73kD

Background： This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Function：similarity:Contains 1 T-box DNA-binding domain.,

Subcellular Location：Nucleus .

Expression：Expressed in CD8+ T-cells.