Target：ENaCδ

Gene Name：SCNN1D

Protein Name：Amiloride-sensitive sodium channel subunit delta

Human Gene Id：6339

Human Swiss Prot No：P51172

Immunogen：The antiserum was produced against synthesized peptide derived from human SCNN1D. AA range:411-460

Specificity：ENaCδ Polyclonal Antibody detects endogenous levels of ENaCδ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SCNN1D;DNACH;Amiloride-sensitive sodium channel subunit delta;Delta-NaCH;Epithelial Na(+) channel subunit delta;Delta-ENaC;ENaCD;Nonvoltage-gated sodium channel 1 subunit delta;SCNED

Observed Band(KD)：70kD

Background：function:Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subunit:Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit.,

Function：function:Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subunit:Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression： Brain,Hippocampus,Lung,Nasal epithelium,Testis,